This paper addresses the place of Northeast Asia regionalism in US foreign policy and defines how much (or little) importance the task of building a regional security architecture is to the United States in its overall East Asia foreign policy agenda. It focuses on the currently ill-fated Six-Party Talks (involving North and South Korea, China, Japan, Russia, and the US) and how this Korean Peninsula denuclearization process both informs and impacts US attitudes toward Northeast Asia regional cooperation.